The Tigers played their home games at Jordan–Hare Stadium in Auburn, Alabama and competed in the Western Division of the Southeastern Conference (SEC).

Shortly after the season, Heisman Trophy finalist junior running back Tre Mason—who broke Bo Jackson's school record for rushing yards in a single season—as well as redshirt sophomore left tackle Greg Robinson declared their intentions to forgo their remaining eligibility and enter the NFL draft.

The 1st team players included QB Nick Marshall, WR Sammie Coates, C Reese Dismukes, DT Gabe Wright.

The 2nd team players included TE CJ Uzomah, OG Alex Kozan (out for season) and ST Robenson Therezie.

3rd team selections were RB Cory Grant, OG Chad Slade, DT Montravius Adams, DE Carl Lawson (out for season), LB Cassanova McKinzy and CB Jonathan Mincy.

Senior starting ST Robenson Therezie faced an undisclosed eligibility issue during fall camp, however he would be cleared to play just prior to the season opener against Arkansas.

Auburn's defense improved greatly in the second half allowing 0 points in that period, forcing several dropped passes to wide open receivers.

Auburn struggled on defense early, giving up some big plays, most notably a 75-yard touchdown pass from Blake Jurich to Tyler Ervin.

On Auburn's first possession Nick Marshall ran 39 yards but lost the ball in the end zone resulting in a touchback.

Auburn was up 24–0 late in the second quarter before Louisiana Tech scored a field goal to end the half.

The defense only allowed one LSU touchdown, taking advantage of Les Miles's decision to have true freshman QB Brandon Harris have his 1st career start on the road at night in JHS.

In the second quarter, Auburn scored 14 more points and the defense held LSU scoreless in that period.

In their weekly "Saturday Selections" segment, David Pollack, Desmond Howard, Lee Corso, and special guest picker Jonathan Papelbon all picked Mississippi State.

The game-changing play was when Ricardo Louis fumbled on a kickoff return leading to a Mississippi State touchdown.

In a game that proved to be a harder challenge than many expected, South Carolina took Auburn down to the wire before the Tiger defense stepped up at the end.

With the victory, Auburn's all-time record against South Carolina moved to 10-1-1. at Vaught–Hemingway Stadium • Oxford, Mississippi

Auburn struck first after an incomplete pass (the official said Duke Williams bobbled it as he was going out of bounds) was reviewed and overturned.

Ole Miss was threatening to score with six and a half minutes to go, but Kris Frost knocked the ball out of Bo Wallace's hands resulting in a turnover for Auburn.

On the Tigers' first offensive possession, Cameron Artis-Payne fumbled the ball and it was recovered by Texas A&M leading to another Aggies score.

On the final play of the second quarter, a Daniel Carlson field goal attempt was blocked and returned for a touchdown making the halftime score Texas A&M 35, Auburn 17.

Penalties, turnovers, man defense in the secondary, an all-in quarterback spy, and the inability to stop Georgia's offense contributed to a 34-7 loss.

Samford coach Pat Sullivan played at Auburn, and was the Tigers' first Heisman Trophy winner.

In the twelfth and final game of the regular season, Auburn traveled to Tuscaloosa to face their arch-rival Alabama.

On the first play from scrimmage, Auburn turned the ball over on a failed lateral from Nick Marshall to Roc Thomas and Alabama scored on the drive after the fumble.

Auburn then scored ten unanswered points before the defense allowed a late Alabama drive for a touchdown on 4th and goal.

At the beginning of the fourth quarter, Alabama scored a touchdown and completed a two-point conversion to take the lead at 42-36.

The Auburn defense was unable to prevent Alabama from rapidly progressing downfield and scoring with a touchdown pass to DeAndrew White.

Saban opted to attempt another 2-point conversion to widen the gap, but this failed when Blake Sims was pushed out of bounds.

at Raymond James Stadium • Tampa, Florida On December 7, it was announced that #19 Auburn and #18 Wisconsin would meet in the Outback Bowl.