The four teams from the four confederations (AFC, CONCACAF, CONMEBOL, and OFC) were drawn into two ties at the World Cup Preliminary Draw at the Marina da Glória in Rio de Janeiro, Brazil, on 30 July 2011.

This was different from previous editions, where the matchups were decided by FIFA beforehand and no draw was held for the inter-confederation play-offs.

The two winners, decided on aggregate score, qualified for the 2014 FIFA World Cup in Brazil.

[1] Uruguay won 5–0 on aggregate and qualified for the 2014 FIFA World Cup.

Mexico won 9–3 on aggregate and qualified for the 2014 FIFA World Cup.