The men's 4 × 100 metre medley relay competition at the 2014 Pan Pacific Swimming Championships took place on August 24 at the Gold Coast Aquatic Centre.

[1] The last champion was the United States.

[2] Prior to this competition, the existing world and Pan Pacific records were as follows: All times are in minutes and seconds.

Heats weren't performed, as only eight teams had entered.

The final was held on August 24, at 21:16.