The Juventus Stadium in Turin, Italy, was chosen as the venue of the match at a UEFA Executive Committee meeting in Istanbul, Turkey, on 20 March 2012.

[10] After a comeback by their opponents Valencia, who had lost the first leg 2–0, Sevilla secured their presence in the final after Stéphane Mbia's injury-time header qualified them on away goals.

[15] It was the first time a club has reached consecutive finals in the competition, having featured in the Champions League group stage on each occasion.

[12] The final was Sevilla's 19th match in the competition, having started their participation in the third qualifying round against Montenegrin side Mladost Podgorica.

They became the first team to reach the Europa League final without conceding a defeat, registering six wins and two draws in eight knockout phase matches.

The second leg at Estádio da Luz ended 0–0, giving Sevilla the victory on aggregate, and they later reached the quarter-finals before losing to eventual champions Real Madrid.

Former Italy international and Juventus player Ciro Ferrara, who won the UEFA Cup in 1989 with Napoli, was named as the ambassador for the final.

[24] Sevilla won the penalty shoot out 4–2, their goals coming from Carlos Bacca, Stéphane Mbia, Coke and Kevin Gameiro.