The 2015–16 season was the 89th season in ACF Fiorentina's history and their 78th in the top-flight of Italian football.

Fiorentina finished the season in 5th place in Serie A, having topped the table early in the season.

In the Coppa Italia, the club was eliminated in the round of 16, losing at home to newly promoted Carpi 1–0.

Competing in the UEFA Europa League for the third season in a row, Fiorentina limped into second place in their group with a 3–1–2 record, and were eliminated in the Round of 32 by Tottenham Hotspur, 4–1 on aggregate.

[2] Montella was replaced by Basel coach Paulo Sousa.