The 2015–16 Campeonato Nacional de Futebol Feminino was the 31st edition of the top division of the Portugal women's football championship.
Viseu 2001 ADSC and União Recreativa Cadima were promoted to the category, replacing Leixões SC and FC Cesarense.
CF Benfica won the championship for the second time and qualified for the Champions League.
Clube de Albergaria was the runner-up, and Valadares Gaia FC was third.
Fundação Laura Santos and Cadima were the teams relegated.