The 2015–16 Cayman Islands Premier League season was the 37th season of top tier Cayman Islands Premier League football competition in the Cayman Islands.
Cayman Brac FC finished 8th at the conclusion of last season and were relegated.
Taking their place in this season was Academy SC.
Roma United finished 7th at the conclusion of last season and had to participate in a play-off, which they won.
Source[1] The 7th place team in this competition will face the runners-up of the First Division for a place in next season's competition.