The 2015–16 College of Charleston Cougars men's basketball team represented the College of Charleston during the 2015–16 NCAA Division I men's basketball season.

The Cougars were led by second-year head coach Earl Grant.

The Cougars played their home games at the TD Arena and were in their third year as members of the Colonial Athletic Association.

They advanced to the quarterfinals of the CAA tournament where they lost to UNC Wilmington.

They advanced to the quarterfinals of the CAA tournament where they lost to UNC Wilmington.