The 2015–16 Cypriot Second Division was the 61st season of the Cypriot second-level football league.
It began on 18 September 2015 and ended on 26 March 2016.
Karmiotissa won their first title.
[2] Teams promoted to 2015–16 Cypriot First Division Teams relegated from 2014–15 Cypriot First Division Teams promoted from 2014–15 Cypriot Third Division Teams relegated to 2015–16 Cypriot Third Division