As the winners of the 2015–16 Eurocup Basketball competition, Galatasaray qualified for the European top-tier level 2016–17 EuroLeague.

[1][2] In July 2015, VEF Rīga, PGE Turów and Juventus withdrew from the competition for join to the FIBA Europe Cup and were replaced by Proximus Spirou, Avtodor Saratov and Szolnoki Olaj.

[3] In August 2015, ČEZ Nymburk and Telenet Oostende withdrew from the competition for join to the FIBA Europe Cup after the draw of Eurocup and were replaced by EWE Baskets Oldenburg and MHP Riesen Ludwigsburg.

For the draw, the teams were seeded into six pots, in accordance with the Club Ranking, based on their performance in European competitions during a three-year period and the lowest possible position that any club from that league can occupy in the draw is calculated by adding the results of the worst performing team from each league.

In the knockout stage, teams played against each other over two legs on a home-and-away basis, with the overall cumulative score determining the winner of a round.