The 2015–16 Guinée Championnat National season was the 49th edition of top level Guinée Championnat National football competition under the authority of Guinean Football Federation in Guinea.
It began on 11 December 2015 and concluded on 27 July 2016.
[1] Horoya AC successfully pursued its 2016 title.
[2] Half of those sides played their home matches in Conakry at Stade du 28 Septembre.
ASFAG and Flamme Olympique FC were promoted from the Championnat National de Ligue 2.