2015–16 Maltese FA Trophy

[1] Birkirkara were the defending champions, but were eliminated in the semi-finals by Sliema Wanderers.

This version of the Maltese FA Trophy was a single elimination tournament contested by 65 teams.

The winner, Sliema Wanderers, earned a spot in the Europa League.

Matches which were level after regulation went to extra time and then penalties to determine a winner.

The last time Balzan and Sliema Wanderers met together in Maltese FA Trophy was during the 2013-14 Fourth round when Sliema Wanderers beat Balzan 8–7 on penalties when the match ends 1–1 draw.