This round featured the bottom 5 teams from the 2014–15 Serbian First League, as well as 5 regional cup winners.
The draw was held on 24 August 2015, and was conducted with the idea of minimizing expenses for the participating clubs.
Drawing of the lots was conducted by former national team player and head coach Ilija Petković.
[4] Seeded teams: Partizan, Red Star Belgrade, Čukarički, Vojvodina, OFK Beograd, Radnički Niš, Jagodina and Spartak Subotica.
The seeds were determined by last season's final standings in the Serbian top divisions.
Drawing of the lots was conducted by former national team player and head coach Slobodan Santrač.
Unseeded teams: Radnički Niš, Spartak Subotica, Borac Čačak and Javor.
[6] Drawing of the lots was conducted by former national team player Jovan Aćimović.
The 4 winners from the Quarter finals(Partizan, Borac Čačak, Spartak Subotica and Javor) took part in the semi-finals.
[9] Drawing of the lots was conducted by national team coach Radovan Ćurčić.