For the Domestic Champions Path, the 32 teams were drawn into two rounds of two-legged home-and-away ties.

[13][14] There were no seedings, but the 32 teams were split into four groups defined by sporting and geographical criteria prior to the draw.

[15] The eight second round winners advanced to the play-offs, where they were joined by the eight group runners-up from the UEFA Champions League Path.

For the knockout phase (round of 16 onwards), the 16 teams were drawn into a single-elimination tournament, with all ties played over one match.

[16][17] The mechanism of the draws for each round was as follows: If the scores were level after full-time, the match was decided by a penalty shoot-out (no extra time was played).

If the scores were level after full-time, the match was decided by a penalty shoot-out (no extra time was played).