Teams played each other twice on a home and away basis, before the league was split into two groups at the end of January 2016 – the top six and the bottom six.

Cefn Druids and Prestatyn Town were relegated out of the Welsh Premier League the previous season, while Llandudno were promoted as winners of the Cymru Alliance and Haverfordwest County were promoted as winners of Welsh Football League Division One.

Teams played each other twice on a home and away basis, before the league split into two groups – the top six and the bottom six.

Teams who finished in positions fourth to seventh at the end of the regular season participated in play-offs to determine the third participant for the 2016–17 UEFA Europa League, who will qualify for the first qualifying round.

[3] The league's rules are contained as a section of the Handbook of the Football Association of Wales.