This season saw the release of president and general manager Dave Dombrowski, who had been with the team since 2002.

In a season plagued by injuries to star players Justin Verlander, Víctor Martínez, Miguel Cabrera, José Iglesias, and Aníbal Sánchez, the Tigers finished in last place in their division with a 74–87 record, had their first losing season since 2008, and failed to make the playoffs for the first time since 2010.

Cabrera did not participate in the All-Star game due to a left calf strain.

[78] The Tigers had a chance to send a fifth player to the All-Star Game this season, as outfielder Yoenis Céspedes was one of the five finalists for the AL in the All-Star Final Vote, but he was beaten out by Mike Moustakas of the Kansas City Royals.

Note: W = Wins; L = Losses; ERA = Earned run average; G = Games pitched; GS = Games started; SV = Saves; IP = Innings pitched; R = Runs allowed; ER = Earned runs allowed; BB = Walks allowed; K = Strikeouts +Totals with Tigers only.