The 2015 Grand Prix Cycliste de Québec was the sixth edition of the Grand Prix Cycliste de Québec one-day cycling race.

It took place on 11 September and was the twenty-fifth race of the 2015 UCI World Tour.

As the Grand Prix Cycliste de Québec was a UCI World Tour event, all 17 UCI ProTeams were invited automatically and obligated to send a squad.

Three UCI Professional Continental teams (Bora-Argon 18, Drapac, and Team Europcar) and a Canadian national squad also competed in the race, and as such, forming the event's 21-team peloton.

This cycling race-related article is a stub.