November 5: Received Carlos Pérez and Nick Tropeano from the Houston Astros for Hank Conger.

November 27: Signed D'Arby Myers to a minor league contract and invited him to spring training.

December 9: Received Drew Butera from the Los Angeles Dodgers for Matt Long.

December 19: Received Johnny Giavotella from the Kansas City Royals for Brian Broderick, while releasing Shawn O'Malley and signing Roberto Baldoquin to a minor league contract.

January 8: Received Kyle Kubitza and Nate Hyatt from the Kansas City Royals for Ricardo Sanchez.

Former Angels general manager Bill Stoneman, who hired Scioscia before the 2000 season, was named interim GM.

In July, the Angels briefly held first place in the AL West before losing 19 games in August.