Michigan was invited to the Citrus Bowl, where they defeated Florida, 41–7, to finish the year with a record of 10–3, and were ranked 12th in the final AP Poll.

As a result of the team's poor record, head coach Brady Hoke was fired on December 2.

The radio announcers were Jim Brandstatter with play-by-play, Dan Dierdorf with color commentary, and Doug Karsch with sideline reports.

Utah dominated the previous meeting, winning 26–10 in a game that featured an almost two-and-a-half hour weather delay.

Michigan added to its lead shortly before halftime with another one-yard touchdown run from Smith, giving it a 17–7 at half-time.

[37] Following the game against Oregon State, Michigan hosted the University of Nevada, Las Vegas (UNLV) Rebels.

After neither team scored in the third quarter, Michigan added to its lead with a one-yard touchdown run from Sione Houma.

UNLV responded with a six-yard touchdown pass from Blake Decker to Devonte Boyd, which ended the scoring.

This was the first meeting between the schools since the 1984 Holiday Bowl, which saw BYU defeat Michigan to clinch that season's national championship.

[49] The game's original kickoff time of 8:00 p.m. was moved forward by eight hours to noon in order to avoid the potential impact of Hurricane Joaquin.

Blake O'Neill placed a punt within the opponent's five yard line for the fourth time in five games.

In the second quarter Jourdan Lewis posted a 37-yard interception return for a touchdown, which made the score 28–0 in favor of Michigan at half-time.

[2] The win marked Michigan's third consecutive shutout, a feat not accomplished by any Football Bowl Subdivision team since Kansas State in 1995.

[60] Due to the quality of and the hype surrounding the matchup between the two teams, the game was selected as the location for ESPN's College GameDay.

Michigan State became the second team in the last two seasons to win a game in regulation in which it did not have the lead until the clock hit 0:00.

Jourdan Lewis matched a program record with six pass breakups, tying Marlin Jackson, who accomplished the feat against the Washington on August 31, 2002.

He owns a total of 14 pass breakups on the season, placing him tied for fourth among Michigan's single-season leaders in the category.

Speight then completed a two-point conversion attempt with a pass to Amara Darboh, giving Michigan a three-point lead.

Jourdan Lewis had one pass breakup to give him 17 on the season, trailing the all-time single-season record held by Marlin Jackson (2002) and Leon Hall (2006) by one.

Michigan added to its lead via a 1-yard touchdown run from Drake Johnson, but Rutgers responded with a 29-yard field by Kyle Federico.

Michigan held Rutgers scoreless during the second half and added to its lead with 14 unanswered points via a 4-yard touchdown run from De'Veon Smith and a two-point conversion run by Jake Ruddock, a 34-yard field goal by Kenny Allen, and a 28-yard field goal by Allen in the fourth quarter.

[73] With his 18th and 19th pass breakups of the season, Jourdan Lewis claimed sole ownership of the single-season Michigan record, which had previously been shared by Leon Hall and Marlin Jackson.

Michigan regained the lead in the fourth quarter with a 20-yard field goal from Allen, but Indiana responded with a 24-yard touchdown run from Howard.

Michigan took the lead in the second overtime via a 25-yard touchdown pass from Rudock to Amara Darboh, and then managed to stop Indiana on a fourth-and-goal attempt from the two-yard line to win the game.

Penn State regained the lead in the second quarter with a 25-yard touchdown pass from Christian Hackenberg to Saeed Blacknail, but Michigan responded with an 11-yard touchdown pass from Rudock to Amara Darboh, which made the score 14–10 in favor of Michigan at half-time.

Penn State reduced Michigan's lead to five points in the fourth quarter with two field goals from Davis, one from 24-yards, and one from 18-yards.

Michigan added the final points of the game in the fourth quarter via a one-yard touchdown run from De'Veon Smith.

[89] Ohio State opened the scoring in the first quarter with a seven-yard touchdown run from J. T. Barrett, but Michigan responded with a 25-yard field goal by Kenny Allen.

Ohio State extended its lead in the second quarter via a five-yard touchdown run from Ezekiel Elliott.

Michigan responded with a five-yard touchdown pass from Jake Rudock to Jehu Chesson, making the score 14–10 in favor of Ohio State at half-time.