His compatriot Mary Jepkosgei Keitany claimed the women's division with a time of 2:24:25, her second consecutive win in New York.
In the opening minutes of the race, the bridge is filled with runners, creating a dramatic spectacle that is closely associated with the event.
At 13.1 miles (21.1 km), runners cross the Pulaski Bridge, marking the halfway point of the race and the entrance into Long Island City, Queens.
[7] By the halfway point (1:12:54), a nine-woman lead pack had emerged led by Portuguese runner Sara Moreira.
They remained together until the 18-mile (29 km) mark, where a group containing Kenyans Mary Jepkosgei Keitany and Priscah Jeptoo, along with Ethiopians Aselefech Mergia and Tigist Tufa started to pull away.
Keitany's win marked the first time a woman had defended the New York Marathon title since Briton Paula Radcliffe in 2008.
At the 20-mile (32 km) mark, the lead pack had reduced to four, containing Kenyans Geoffrey Kamworor, Stanley Biwott and Wilson Kipsang Kiprotich, along with Desisa.
[2] Former professional tennis player James Blake finished the course in 3:51:19 and actor Ethan Hawke recorded a time of 4:25:30.