The 2015 Penn Quakers football team represented the University of Pennsylvania during the 2015 NCAA Division I FCS football season.

They were led by first-year head coach Ray Priore and played their home games at Franklin Field.

They were a member of the Ivy League.

They finished the season 7–3 overall 6–1 in Ivy League play to place in a three-way tie for the Ivy League title with Dartmouth and Harvard.

Penn averaged 6,048 fans per gam.