The 2015 Regional League Division 2 (also known as the AIS Regional League Division 2 for sponsorship reasons) was the 10th season of the Regional League Division 2, it had redirected from the division 2, since its establishment in 2006.
The 83 clubs in Thailand will be divided into 6 groups (regions) red Zone : 2015 Regional League Division 2 Bangkok Metropolitan Region Yellow Zone : 2015 Regional League Division 2 Central & Eastern Region Pink Zone: 2015 Regional League Division 2 Central & Western Region Green Zone: 2015 Regional League Division 2 Northern Region Orange Zone: 2015 Regional League Division 2 North Eastern Region Blue Zone: 2015 Regional League Division 2 Southern Region
Ubon UMT United won 9–0 on aggregate.
The Regional Division 2 2015 winners were Ubon UMT United F.C.