2015 Regional League Division 2 Central & Western Region is the 3rd season of the League competition since its establishment in 2013.
It is in the third tier of the Thai football league system.
No club was promoted to the Thai Division 1 League.
Last years league champions Hua Hin and runners up Phetchaburi failed to qualify from the 2014 Regional League Division 2 championsleague round.
Simork joined the newly expanded league setup.