Defending champion Novak Djokovic defeated Roger Federer in a rematch of the previous year's final, 7–6(7–1), 6–7(10–12), 6–4, 6–3 to win the gentlemen's singles tennis title at the 2015 Wimbledon Championships.

Brown previously defeated Nadal on a grass court just a year prior at the Gerry Weber Open, the only other time the two had played each other.

This marked the fourth straight year in which Nadal suffered an early exit from the tournament by losing to a player ranked outside the world's top 100.

8 David Ferrer did not participate (due to an elbow injury), ending his streak of 50 consecutive major appearances.

This was also the first major main draw appearance for future two-time ATP Finals champion and Olympic gold medalist Alexander Zverev; he lost to Denis Kudla in the second round.