The playoffs involved the twenty four teams which qualified as winners and runners-up, of each of the four groups in the 2016–17 Basketball Champions League Regular season.
Each tie in the playoffs, apart from the Final Four games, was played with two legs, with each team playing one leg at home.
The team that scored more points on aggregate, over the two legs, advanced to the next round.
The five group winners, and the three best runner-up teams, were directly qualified for the round of 16, while the other sixteen teams were drawn against each other.
For the first phase and the round of 16, teams from the same country could not be drawn against each other.