[2] On 2 July, the club's president Eduardo Atala confirmed an exhibition game against current Copa Libertadores winners at that time and South American giants River Plate.

[3] The Apertura schedule was unveiled on the second week of July and the club decided to return their home games on Sundays afternoon[4] after their last season experiment of playing on Saturdays seeking for better assistances didn't throw the expected results.

Social Sol at home; in the 50' minute (0–0), the referee decided to suspend the match due to heavy rain which caused a power outage.

Marathón away in postseason for the first time since November 1990;[9] however, the access to the semifinals didn't turn out that easy as Motagua had to rely on a late and controversial penalty in the second leg to advance with a 3–3 global score.

[10] In the semifinals Motagua faced city rivals Club Deportivo Olimpia for another edition of the Honduran Superclásico, resulting in the fourth time these two teams meet in this stage in the last three years.

for the first round of the 2017 Honduran Cup, a competition which ended way too early for Motagua's aspirations as they lost in penalty shootouts against a club that plays in third division.

On 13 March, the club announced through their social media that Argentinian midfielder Santiago Vergara was being treated in a local health center as he was diagnosed with leukemia.

Despite losing key players from their roster, Motagua was capable of finishing the Clausura tournament with 14 unbeaten games in a row, a performance that resulted in their 15th league championship and a season's double.

Before the start of the final match against Honduras Progreso, the selling of fake tickets in the black market triggered a chaos among the fans inside and outside the stadium.