The 2016–17 Canisius Golden Griffins men's basketball team represented Canisius College during the 2016–17 NCAA Division I men's basketball season.

The Golden Griffins, led by first-year head coach Reggie Witherspoon, played their home games at the Koessler Athletic Center in Buffalo, New York as members of the Metro Atlantic Athletic Conference.

They defeated Marist in the first round of the MAAC tournament to advance to the Quarterfinals where they lost to Saint Peter's.

They defeated Niagara in the first round of the MAAC tournament to advance to the Quarterfinals where they lost to Iona.

On May 28, the school hired Reggie Witherspoon as head coach.