The 2016–17 Deportivo de La Coruña season was the club's 110th in its history and its 45th in La Liga, the top-tier of Spanish football.

In addition to the domestic league, the club also competed in the 2016–17 Copa del Rey.

[1] Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.