The 2016–17 División de Honor was the 50th season of the top flight of the Spanish domestic rugby union competition since its inception in 1953.

Valladolid won the title, its seventh overall after defeating local arch-rivals El Salvador in the Final.

The season took place between September and March, with every team playing each other home and away for a total of 22 matches.

The relegation playoff was played over two legs by Getxo Artea, the team finishing 11th in División de Honor, and UBU-Colina Clinic, the losing team from División de Honor B promotion playoff final.

Getxo Artea won 132-19 on aggregate and remained in the División de Honor A.