On 14 July 2016, Partizan opened season with a 0–0 home draw against Zagłębie Lubin in second qualifying round for the UEFA Europa League.

[5] On 4 August 2016, coach Marko Nikolić returned to Partizan on a two-year deal.

Partizan made six consecutive wins before he draw (1–1) against Radnički Niš at home, on 22 October.

[9] After that match, Partizan made four more consecutive wins before he draw (0–0) against Vojvodina at Karađorđe Stadium, on 30 November.

[12] On 4 March, Partizan drew 1–1 at Rajko Mitić Stadium, in Eternal derby, against Red Star.

On 18 April, in first match of play-off, Partizan made a huge victory at Rajko Mitić Stadium, in Eternal derby, against Red Star.

[18] On 21 May, Partizan beat Mladost Lučani 5–0 at home in front of 26,785 fans and won 27th title.