The 2016–17 Louisville Cardinals men's basketball team represented the University of Louisville during the 2016–17 NCAA Division I men's basketball season.

The Cardinals competed in the Atlantic Coast Conference and were coached by Rick Pitino, in his 16th and final season at Louisville.

The team played its home games on Denny Crum Court at the KFC Yum!

They received an at-large bid to the NCAA tournament where they defeated Jacksonville State in the first round to advance to the second round where they lost to Michigan.

The University of Louisville self-imposed a postseason ban for the 2015–16 season amid an ongoing NCAA investigation over an escort sex scandal involving recruits between 2010 and 2014.