The 2016–17 Macedonian Football Cup was the 25th season of Macedonia's football knockout competition.
[1] Shkëndija are the defending champions, having won their first title in the previous year.
Mladost Carev Dvor withdrew from the competition, so their opponents Metalurg got a bye to the next round.
The draw was held on 2 September 2016.
The first legs were played on 1 March 2017 and the return legs played on 19 April 2017.