Ten teams from seven countries (Belarus, Bosnia and Herzegovina, Croatia, Hungary, Macedonia, Slovakia and Slovenia) participated in that year's competition.

The SEHA League was consisted of two phases – the first has 18 rounds in which all teams play one home and one away game against each other.

The campaign began on 30 August 2016 with the match between last year's runner up Vardar and fourth placed Meshkov Brest.

The regular season ended on 16 March 2017, with the decisive match between PPD Zagreb and Meshkov Brest.

Following is the list of clubs competing in 2016–17 SEHA League, with their manager, team captain, kit manufacturer and shirt sponsor.