The 2016–17 USC Trojans women's basketball team represented University of Southern California during the 2016–17 NCAA Division I women's basketball season.

The Trojans, led by fourth year head coach Cynthia Cooper-Dyke, played their home games at the Galen Center and were members of the Pac-12 Conference.

They lost in the first round Pac-12 women's basketball tournament to California.

On March 3, Cynthia Cooper-Duke resigned.

[1] She finished at USC with a four-year record of 70–57.