The Huskies, led by fourth year head coach Mike Neighbors, played their home games at Alaska Airlines Arena and were members of the Pac-12 Conference.

In the final regular season game for the Huskies on February 25, 2017, Kelsey Plum scored a Pac-12 record 57 points in an 84–77 win over Utah to set NCAA Division I women's basketball career scoring record.

They were upset by the 10 seed Oregon in the quarterfinals of Pac-12 women's tournament.

They received an at-large bid of the NCAA women's tournament where they defeated Montana State and Oklahoma in the first and second rounds before losing to Mississippi State in the sweet sixteen.

On April 3, Mike Neighbors resigned from Washington to accept the head coaching job at Arkansas.