The Tigers played their home games at Jordan–Hare Stadium in Auburn, Alabama and competed in the Western Division of the Southeastern Conference (SEC).

Following the 2015 season, defensive coordinator Will Muschamp left the program to become the head coach at South Carolina, joining him were Travaris Robinson, Lance Thompson, JB Grimes moved on as well to join Cincinnati's coaching staff.

Kevin Steele was hired to be Auburn's new defensive coordinator, and assistants Wesley McGriff, Travis Williams, and Herb Hand were added to the staff.

The offseason saw numerous transfers including: RB Roc Thomas, TE Chris Laye, OL Jordan Diamond, OL Will Adams, DE Gimel President, LB Javiere Mitchell and S Tim Irvin.

Auburn picked up transfers in Baylor RB Kameron Martin, Illinois LB TJ Neal and Miami, OH CB Marshall Taylor.

Texas RT Darius James and Ohio St CB Jamel Dean now available after sitting out 2015.

45,723 fans came to see the Tigers perform, making this the lowest attendance for 'A-Day' in the Gus Malzahn era.

The Tigers hosted SEC foes Arkansas, LSU, Texas A&M, and Vanderbilt, and traveled to Alabama, Georgia, Mississippi State, and Ole Miss.

Auburn cut the lead on another field goal by Daniel Carlson, but once again Clemson responded with another touchdown.

Auburn scored first but Arkansas State quickly answered with a long pass play that set up a touchdown to tie the game at 7.

Sean White had 3 touchdowns, and the game was Auburn's best offensive performance, according to many writers, since the 2014 season.

After an illegal shift was called against LSU with one second to go, LSU would go on to score what was initially called a touchdown as time expired before being reviewed and determined that time expired prior to the snap, negating the touchdown and giving Auburn the 18–13 win.

Auburn held LSU star running back Leonard Fournette to less than half the yards they allowed him in 2015.

The last time the Warhawks and the Tigers clashed, the result was a 31–28 Auburn victory in overtime back in the 2012 season.

It broke a two-game losing streak to the Bulldogs and improved Auburn's record to 4–2 and 2–1 in the SEC.

After their only bye week of the season, Auburn played Arkansas in the seventh game of the year.

The eighth game of the season was a trip to Oxford, Mississippi to face Ole Miss.

The key play came late in the game with Auburn leading 33–29 and Ole Miss driving down the field for the go-ahead touchdown.

Ole Miss tight end Evan Engram dropped a pass which would have likely resulted in a touchdown.

On the next play, Auburn defender Josh Holsey intercepted quarterback Chad Kelly's pass and returned it the Ole Miss 30 yard line.

That set up a Kerryon Johnson touchdown that made it a two possession game, ultimately sealing the win for Auburn.

The final game of the regular season is the annual Iron Bowl clash with Alabama.