Although not a save situation, Kimbrel made his Red Sox debut in the ninth and shut the door, allowing a walk and striking out two.

The next day, Clay Buchholz's instability was exposed as he gave up a game-winning grand slam to Colby Rasmus in the 6th inning of the Red Sox's loss.

Atlanta Coming in late to a home-and-home 4-game series against the league's worst team, the Red Sox bats were unable to score against Braves ace Julio Teherán.

The Red Sox offense remained scoreless until the 7th inning, when Jackie Bradley Jr. continued his week of clutch hitting with a first-pitch 2 RBI double off the Green Monster.

But the offense continued to perform well when David Ortiz hit a towering 2-run home run to center off of elite setup man Dellin Betances, who had a sub-1.00 ERA and a 20 K/9 rate entering the game.

Rick Porcello went 7 shutout innings to improve to 5–0 and Robbie Ross Jr. and Junichi Tazawa held New York scoreless in an 8–0 win to wrap up the month of April.

The Red Sox completed the three-game sweep with the help of a Christian Vázquez home run in the seventh off of Dellin Betances, who posted an 0.9 ERA and 0.8 WHIP before the series.

The Red Sox extended their home run streak to 19 games on a Jackie Bradley Jr. solo shot in the second inning and never looked back to avoid the sweep.

In game two, after returning from the DL with a right shoulder impingement, starting pitcher Joe Kelly took a no-hitter through 6+2⁄3 IP against the Cleveland Indians until Juan Uribe broke it up with a double.

After two quick outs in the bottom of the inning and two times down to their last strike, Kimbrel gave up three consecutive hits and the Blue Jays walked off.

But it was for naught, when Max Kepler belted a 0–2 fastball by Matt Barnes over the wall in right center field for his first career-home run and the Twins walked off as winners.

Shields was pulled after allowing back-to-back walks with 0 outs, both runners eventually scored and Boston subsequently put a four spot on the board.

In the top of the tenth, the White Sox again had the bases loaded with nobody out, and again the Boston pitcher responsible for his own mess, Craig Kimbrel, escaped unscathed.

Down to the last strike, Sandy León doubled after an eleven-pitch at bat to drive in Jackie Bradley Jr. Mookie Betts went deep and the game was tied.

Steven Wright allowed eight runs in his 4 2⁄3 innings of work, but only three of them were earned, due to errors by Xander Bogaerts and Hanley Ramírez, and a passed ball by catcher Christian Vázquez.

Red Sox won the series 2–1 (17–30 runs) July 4–6, vs. Texas The Rangers got early to Rick Porcello and scored four times in the first.

Red Sox won the series 2–1 (11–8 runs) July 19–20, vs. San Francisco Rick Porcello dealt 6 1⁄3 scoreless innings, against the majors leading Giants.

Drew Pomeranz made his Red Sox debut, but lasted only three innings, facing seven batters and giving up five runs in the fourth without recording an out.

Red Sox lost the series 1–2 (14–11 runs) August 9–11, vs. New York Rick Porcello earned his 100th career win in his third straight start with 8 innings or more of work.

With 2015 Cy Young runner-up Zack Greinke on the mound for Arizona, the Diamondbacks tried to avoid the sweep but Boston's offense chased him from the game after just 1 2⁄3 innings, allowing nine runs on ten hits.

Pomeranz was credited with his first win for the Red Sox thanks to a two-run shot by David Ortiz and a solo home run by Jackie Bradley Jr. in the sixth inning.

Red Sox won the series 1–0 (3–2 runs) August 16–17, in Baltimore Eduardo Rodríguez tossed 4 hitless innings before he was pulled with left hamstring tightness.

With the win, the Red Sox put the Orioles to third place in the AL East for the first this season and are one game behind the division leading Blue Jays.

With two outs in the bottom of the eleventh, Heat Hembree missed a catch at first base and his quick throw to the plate could not be scooped up by catcher Sandy León, allowing the walk-off run to score.

Red Sox lost the series 1–2 (15–19 runs) August 29–31, vs. Tampa Bay Rick Porcello remained perfect at home and earned his major league leading 18th win.

With a second late inning meltdown in a row looming, the bats stepped up with three consecutive, one-out hits to score Hanley Ramírez and Brock Holt.

He received no run support and Craig Kimbrel was charged with the loss after he allowed a lead-off walk and a mishandled base hit by Brock Holt into left field.

Red Sox won the series 2–1 (26–14 runs) September 12–14, vs. Baltimore Boston scored four times after only 11 pitches by former teammate Wade Miley.

John Farrell let David Price pitch into the seventh inning and gave up three hits, including a two-run home run, before recording one out and he was done for the night.

Composite line score Total 8:08 p.m. (EDT) at Progressive Field in Cleveland, Ohio The Red Sox jumped out to a first inning 1–0 lead, but Rick Porcello's 22–4 regular season record would prove irrelevant as he couldn't contain the Tribe offense.