2016 Citi Open – Men's singles

Kei Nishikori was the defending champion, but chose not to participate this year.

Second-seeded Gaël Monfils won the title, defeating Ivo Karlović in the final: 5–7, 7–6(8–6), 6–4.

All seeds receive a bye into the second round.

Click on the seed number of a player to go to their draw section.

The top four seeds received a bye into the qualifying competition.