On 21 October 2016, a Camrail inter-city passenger train travelling from Cameroon's capital, Yaoundé, to its largest city, Douala, derailed in Eséka, Centre Region.

[6] The passenger train involved in the crash was travelling on a Camrail line between the capital, Yaoundé, and the country's largest city and economic hub, Douala.

[7] A Reuters journalist travelling on the train reported a loud noise and smoke as several of the carriages derailed around midday local time (11:00 GMT) in Eséka, about 120 km (75 mi) west of the capital.

[8] In the immediate aftermath of the crash, Camrail announced they will send investigative teams to the site, and expressed their condolences to the victims' families in a post on the company's official Facebook page.

Reuters reported that at least one of the four confidential investigations found that Camrail had "total and entire responsibility" for crash and that the railroad had improperly inspected the train before its doomed journey.