The 2016 Grand Prix Cycliste de Québec is the 7th edition of the Grand Prix Cycliste de Québec road bicycle race.

The race took place on 9 September 2016, and was won by Peter Sagan in the sprint before Greg Van Avermaet and Anthony Roux.

[1] The 18 UCI World Tour teams are automatically entitled and obliged to start the race.

The race organisation gave out two wildcards to UCI Professional Continental teams.

This cycling race-related article is a stub.