The team won its remaining regular season games, and finished conference play with an overtime victory against third-ranked Michigan.

On defense, cornerback Malik Hooker led the Big Ten with seven interceptions (three returned for a touchdown) and was also a unanimous first-team All-American.

Ohio State's offense started off slow by QB, J. T. Barrett throwing an interception returned for a touchdown to Brandon Harris.

Ohio State then went on to score 21 unanswered points before BGSU made a field goal midway through the second quarter.

Ohio State was unable to find their way into the endzone and settled for a 29-yard Tyler Durbin field goal to make the score 3–0.

The Silver Bullet defense of Ohio State forced two second-half turnovers and allowed no offensive points from the Golden Hurricane.

During the ensuing kickoff, Oklahoma's Joe Mixon returned the kick for a 97-yard touchdown, to make the score 14–7, Ohio State.

With six minutes to go in the half, Oklahoma scored on a 35-yard Mayfield pass to A.D. Miller to give the OSU defense their first allowed offensive touchdown of the year and brought the Sooners within 11.

Ohio State scored on their opening possession of the half with Noah Brown's school record tying fourth touchdown reception.

Baker Mayfield (the Sooners starting QB) claimed that the Ohio State team and fans who traveled to Norman sang their fight song after their win.

Baker Mayfield cites this as his reasoning for spiking the flag on the Ohio State symbol at the 50 yard line in the 2017 rematch in Columbus.

Neither team could find the endzone for the remainder of the first half and both settled for two additional field goals apiece for a halftime score of 16–6 favoring the Badgers.

On Barrett's second touchdown, Ohio State took their first lead of the night at the 14:09 mark of the fourth quarter, and the Buckeyes led 20–16.

The Badger offense drove 25 yards on their last possession, but come up short of field goal range and had to punt to the Buckeyes with 0:14 left.

Ohio State would get the ball first in overtime and would score a touchdown on a J. T. Barrett pass to Noah Brown on third and two from the Wisconsin 7, which gave them a 30–23 lead.

Wisconsin opted for a pass and Hornibrook was sacked by Tyquan Lewis to preserve Ohio State's unbeaten status.

Wisconsin Junior Linebacker Jack Cichy, who had 15 tackles, one sack and a forced fumble, was named Big Ten Defensive Player of the Week for his performance.

The Buckeyes started off the game quickly by scoring ten unanswered points in the first quarter with a Mike Weber touchdown run and a 35-yard Tyler Durbin field goal following an Ohio State interception.

The Wildcats inched closer by scoring at the 14:51 mark of the second quarter, but it was followed by another Weber touchdown run of 23 yards.

With 1:23 left in the half, Northwestern made a 23-yard field goal to make the halftime score 17–10, Ohio State.

He was carried off of the field on a stretcher and transported to Ohio State University Wexner Medical Center for evaluation.

Ohio State would receive the ball in the third quarter and would score on the opening play with a 75-yard pass from J. T. Barrett to Curtis Samuel.

Ohio State's offense would score 17 more points in the game and defensive back Malik Hooker would record his second interception returned for a touchdown and fifth overall for the season.

[29] Curtis Samuel was named Big Ten Conference Co-offensive Player of the Week for his performance by gaining 173 all-purpose yards and two touchdowns.

Michigan State received the opening kickoff and in two plays scored a 64-yard touchdown screen pass from Tyler O'Connor to L. J. Scott to give the Spartans a 7–0 advantage 46 seconds into the game.

On third and three at the MSU 16, Mike Weber fumbled the ball giving Ohio State no chance to attempt a field goal.

Both teams punted twice to start the second half until Ohio State formed a four-play 69-yard drive that resulted in another touchdown, giving them a 17–10 advantage.

Ohio State reduced Michigan's lead to three points via a one-yard touchdown run from Mike Weber, before Tyler Durbin recorded a 23-yard field goal as time expired in the fourth quarter to tie the game and force overtime.

On a controversial 4th and 1 play, J.T Barrett ran up the middle and was tackled in such a way that the forward progress made it difficult to determine where the ball would be spotted.

Darboh has recorded a reception in 32 consecutive games, earning a share of the fourth spot among Michigan's all-time leaders in the category.