Maria Isabelle Climaco Salazar Liberal Maria Isabelle Climaco Salazar Liberal Local elections were held in Zamboanga City on May 9, 2016, within the Philippine general election.

District II Representative Lilia Macrohon-Nuño is running for reelection.

Incumbent Mayor Maria Isabelle Climaco Salazar is running for reelection.

Incumbent Vice Mayor Cesar Iturralde is running for reelection.

Although he considered to run for Congress representing District 2, Iturralde decided to back down in attempt to prevent a show-off between incumbent Mayor Beng Climaco and incumbent 1st district representative Celso Lobregat.