Pavel Vrba returned to manage the club in the summer of 2017.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Source: See results As a result of losing the third qualifying round, FC Viktoria Plzeň was moved to the play-off round of the Europa League.