Umana Reyer Venezia won its first European competition, after defeating Sidigas Scandone in the all-Italian Finals.

The three teams with the smallest point difference in the second qualifying round advanced to the regular season.

The draw for the regular season was held on 3 August 2017 at the FIBA headquarters in Munich, Germany.

A total of 32 teams play in the regular season: the ten winners of the play-off round, the 19 of 24 losers of the 2017–18 Champions League qualifying rounds and the three lucky losers who replaced the defeated teams that used their opt-out clause.

In other words, the following nine teams ended their continental adventure when they were eliminated from the main continental competition organized under the aegis of FIBA and therefore refuse to participate in the FIBA Europe Cup:[3][4] Depending on the number of teams mentioned above that were eliminated from the Basketball Champions League qualifying rounds and with the aim to complete the 32 places in the regular season, the number of the defeated teams in the second qualifying round of the FIBA Europe Cup that advanced to the regular season were determined by the point difference recorded at the end of their pairings.

A total of 16 teams play in the second round: the eight group winners and the eight runners-up of the regular season.

[6] Movistar Estudiantes, Élan Chalon, AEK Athens and SIG Strasbourg, had opt-out clauses from playing in the FIBA Europe Cup and in the event of them claiming fifth or sixth place, their spot would be filled by the best-ranked third-placed teams from the second round.

After each gameday a selection of five players with the highest efficiency ratings is made by the FIBA Europe Cup.