The play-offs involves 16 teams which qualified as winners or second placed of each one of the four groups in the second round.
If a FIBA Europe Cup team is drawn against a Basketball Champions League team, the FIBA Europe Cup side would have the home-court advantage in the second leg.
[1] The four group winners and second-placed teams from the second round advanced to the play-offs.
Eight teams from the 2017–18 Basketball Champions League Regular season transfer to the FIBA Europe Cup.
Movistar Estudiantes, Élan Chalon, AEK Athens and SIG Strasbourg, had opt-out clauses from playing in the FIBA Europe Cup and in the event of them claiming fifth or sixth place, their spot would be filled by the best-ranked third-placed teams from the second round.