The Blasters also made their debut in the inaugural edition of Super Cup during the season, being eliminated in the first round after losing against NEROCA.

Following the departure of Steve Coppell to the new side Jamshedpur, Kerala Blasters announced the signing of René Meulensteen as their new head coach on 14 July 2017.

Former Kerala Blasters forward Iain Hume rejoined the side in July while the club also signed former Manchester United players Wes Brown and Dimitar Berbatov in the lead up to the season.

[8][9] "In terms of selection of players, we were looking at him for quite sometime," said Varun Tripuraneni, the Kerala Blasters CEO, "After Rene Meulensteen came on board, it became easier to get the deal done.

However, in the 77th minute, Mumbai City found an equalizer through Balwant Singh and the match ended 1–1 - a third draw in a row at home.

Vineeth, who returned from suspension, scored the only goal of the match in the 24th minute from a header which came from a Rino Anto cross.

[34] The Kerala Blasters then ended the year with another 'Southern Derby" match against new expansion side Bengaluru at the Nehru Stadium.

However, in the 60th minute, Blasters captain Sandesh Jhingan handled the ball in the penalty box after a cross from Udanta Singh.

[39] Also on that day, the club announced the signing of their eighth foreigner, midfielder Kizito Keziron from Leopards in Kenya.

Iain Hume opened the scoring for the Blasters in the 12th minute when he put in a squared ball from Courage Pekuson.

Jerry Mawihmingthanga opened the scoring for Jamshedpur in the very first minute when he converted what was a scuffed shot from teammate Ashim Biswas.

Mark Sifneos found a consolation goal for the Blasters three minutes into second half stoppage time but it was too late to save the match.

David James decided to go with only four foreigners on the pitch for Kerala and it proved a bad choice only seven minutes into the match as Coro found the net.

Vineeth managed to find Kerala's equalizer after he exploited the space left by the Goan defenders in the middle.

Coming into the match, the Blasters had released Dutch striker Mark Sifneos and signed former Iceland international Guðjón Baldvinsson as a replacement.

At halftime, James took off Karan Sawhney and brought on 19-year old Deependra Negi for his professional debut and three minutes into the second half the former India U17 captain scored the equalizer for the Kerala Blasters from a corner.

[47] On 2 February 2018, the Kerala Blasters played their first match of the last full month of the season against Pune City at the Balewadi Stadium.

Despite Guðjón Baldvinsson and Dimitar Berbatov scoring their first goals for the club, both times giving the team the lead, the Blasters conceded twice to draw the match 2–2.

[49] The Kerala Blasters then ended their three game away run with a victory against NorthEast United on 17 February 2018 at the Indira Gandhi Athletic Stadium.

Neither side could find the net in the 0–0 draw as the Blasters' chance of qualification for the finals suffered a massive blow.

[53] As the Kerala Blasters finished in sixth place during the 2017–18 ISL season, they entered the main competition directly which was hosted at the Kalinga Stadium in Bhubaneswar.

[57] Goals for NEROCA were scored by Jean-Michel Joachim, Aryn Williams, and Felix Chidi Odili while Kerala Blasters found the net through Pulga and Prasanth Karuthadathkuni.