All ties level after 90 minutes used extra time to determine the winner, with a penalty shoot-out to follow if necessary.

Teams that finished higher on the league in the previous season played their ties away.

Teams that finished higher on the league in the previous season played their ties away.

All matches were played on 25 July 2017.Speranța Drochia, Rîșcani, Intersport Sănătăuca, FCM Ungheni, Socol Copceac, Fortuna Pleșeni and Olimp Comrat received a bye for the second preliminary round.

The 8 winners from the previous round joined the 2 Divizia Națională sides seeded 9-10, Sfîntul Gheorghe and Spicul Chișcăreni.

The home teams and the pairs for 2 Divizia Națională sides were determined in a draw held on 16 August 2017.

The 5 winners from the previous round and Steaua-57 Chișinău, Victoria Bardar, Sokol Copceac joined the remaining 8 Divizia Națională sides seeded 1-8.