The 2017–18 season was PAOK Football Club's 92nd in existence and the club's 59th consecutive season in the top flight of Greek football.

The season was marked by two derby matches (vs Olympiacos on 25 February and vs AEK on 11 March) that were awarded against PAOK by court decision.

The team defended their Greek Cup title won in 2017 and also competed in UEFA Europa League.

Source: Competitions Source: Competitive matches Note: PAOK were deducted 3 points by court decision.

Win Draw Loss Win Draw Loss Win Draw Loss Appearances denote players in the starting lineup, with the numbers in parentheses denoting appearances as substitute.