The 2017–18 season was SPAL's first season in the top-flight of Italian football since 1968.

The team were promoted as champions of Serie B.

The club finished just above the relegation places, in 17th, securing a second season of Serie A football for the 2018–19 campaign; SPAL were eliminated in the fourth round of the Coppa Italia.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Players may hold more than one non-FIFA nationality.