Star forward Kawhi Leonard played a career-low nine games during the season due to a quadriceps injury.
On March 10, 2018, the Spurs finished with a losing season on the road for the first time since 1997 after a loss to the Oklahoma City Thunder.
The Spurs clinched a playoff spot on April 9, 2018, with a win over the Sacramento Kings in their last home game of the season.
On July 18, 2018, Leonard and Danny Green were traded to the Toronto Raptors, for DeMar DeRozan, Jakob Pöltl, and a first-round draft pick.
This marked the official end of the Spurs' "Big Three" era; the trio of Parker, Ginobili, and Tim Duncan won a total of four NBA championships together during their years with the team.